How GPT-5 helped immunologist Derya Unutmaz solve a 3-year-old mystery

Immunologist Derya Unutmaz used GPT-5 Pro to work through a longstanding puzzle in T cell behavior, arriving at insights that could inform future cancer and autoimmune research. The account is compelling not as a claim of AI sentience or scientific autonomy, but as a concrete example of a domain expert using a language model as a thinking partner for hypothesis generation. It is worth reading with both genuine curiosity and a steady eye toward what remains unverified — reproducibility and peer review have not yet entered this story.